Rett syndrome is a rare neurological condition that primarily affects girls and is most often caused by a mutation in the MECP2 gene. Children with Rett syndrome typically develop normally in their first year, before gradually losing previously acquired skills such as speech, purposeful hand use, and coordination.

As the condition progresses, it can affect nearly every aspect of a person’s daily life—from walking and eating to breathing and communicating. Though the challenges are significant, supportive care and inclusive attitudes can help individuals with Rett syndrome live meaningful, connected lives.